Rare consecutive femoral lesser trochanteric avulsion in an adolescent following sporting activities; a case report

Avulsion of the lesser trochanter is a rare but disturbing condition, which usually occurs in males between the ages of 7-16 years with significant physical activities or in athletes.Diagnosis is more often than not challenging, but with a good history, physical examination, and imaging modality, diagnosis can be clinched, and the prognosis is good

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The DNMT3A PWWP domain is essential for the normal DNA methylation landscape in mouse somatic cells and oocytes.

DNA methylation at CG sites is important for gene regulation and embryonic development.In mouse verona wig oocytes, de novo CG methylation requires preceding transcription-coupled histone mark H3K36me3 and is mediated by a DNA methyltransferase DNMT3A.DNMT3A has a PWWP domain, which recognizes H3K36me2/3, and heterozygous mutations in this domain,

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